Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.A107S

c.319G>T

Surrounding Variants

2 papers

NM_001382430.1

p.A107D

c.320C>A

3 papers

NM_001382430.1

p.V106L

c.316G>T

1 paper

NM_001382430.1

p.D108Y

c.322G>T

1 paper

NM_001382430.1

p.T105delFs

c.314_315delAG

1 paper

NM_001382430.1

p.A102_D108insFs

c.304_323dup20

1 paper

NM_001382430.1

p.Q104delFs

c.311_312delCT

2 papers

NM_001382430.1

p.G109S

c.325G>A

5 papers

NM_001382430.1

p.T105A

c.313A>G

1 paper

NM_001382430.1

p.I103_Q104delFs

c.309_312del4

2 papers

NM_001382430.1

p.G109V

c.326G>T

1 paper

NM_001382430.1

p.G109G

c.327C>T

1 paper

NM_001382430.1

p.G109delFs

c.325delC