Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.Q104R

c.311A>G

Surrounding Variants

1 paper

NM_001382430.1

p.Q104*

c.310C>T

2 papers

NM_001382430.1

p.Q104K

c.310C>A

1 paper

NM_001382430.1

p.T101_I103del0

c.303_308del6

1 paper

NM_001382430.1

p.I103I

c.309C>A

5 papers

NM_001382430.1

p.T105A

c.313A>G

1 paper

NM_001382430.1

p.I103_Q104delFs

c.309_312del4

36 papers

NM_001382430.1

p.I103N

c.308T>A

1 paper

NM_001382430.1

p.A102_I103del1

c.305_307delTGG

1 paper

NM_001382430.1

p.Q104delFs

c.311_312delCT

1 paper

NM_001382430.1

p.I103V

c.307A>G

3 papers

NM_001382430.1

p.V106L

c.316G>T

1 paper

NM_001382430.1

p.T105delFs

c.314_315delAG