Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.T101N

c.302C>A

Surrounding Variants

2 papers

NM_001382430.1

p.T101I

c.302C>T

1 paper

NM_001382430.1

p.T101S

c.301A>T

4 papers

NM_001382430.1

p.T101A

c.301A>G

1 paper

NM_001382430.1

p.T101P

c.301A>C

3 papers

NM_001382430.1

p.A102V

c.305C>T

1 paper

NM_001382430.1

p.T100I

c.299C>T

1 paper

NM_001382430.1

p.W99*

c.297G>A

1 paper

NM_001382430.1

p.I103V

c.307A>G

36 papers

NM_001382430.1

p.I103N

c.308T>A

1 paper

NM_001382430.1

p.A102_I103del1

c.305_307delTGG

1 paper

NM_001382430.1

p.W99*

c.296G>A

1 paper

NM_001382430.1

p.W99R

c.295T>C