Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.E97fs

c.289_290fs

Surrounding Variants

1 paper

NM_001382430.1

p.R96R

c.288G>T

1 paper

NM_001382430.1

p.R96R

c.288G>A

3 papers

NM_001382430.1

p.R96Q

c.287G>A

1 paper

NM_001382430.1

p.E98*

c.292G>T

2 papers

NM_001382430.1

p.E98Q

c.292G>C

1 paper

NM_001382430.1

p.E98K

c.292G>A

3 papers

NM_001382430.1

p.R96W

c.286C>T

1 paper

NM_001382430.1

p.R96Splc

c.288-3C>T

1 paper

NM_001382430.1

p.E98G

c.293A>G

1 paper

NM_001382430.1

p.W99R

c.295T>C

2 papers

NM_001382430.1

p.W99R

c.295T>A

1 paper

NM_001382430.1

p.W99*

c.296G>A