Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.F88L

c.264C>G

Surrounding Variants

1 paper

NM_001382430.1

p.F88_H89insFs

c.264_265insGT

1 paper

NM_001382430.1

p.F88L

c.264C>A

1 paper

NM_001382430.1

p.F88L

c.262T>C

1 paper

NM_001382430.1

p.I84_T87del4

c.250_260del12

1 paper

NM_001382430.1

p.H89L

c.266A>T

1 paper

NM_001382430.1

p.H89Q

c.267T>G

1 paper

NM_001382430.1

p.H89Q

c.267T>A

2 papers

NM_001382430.1

p.V90L

c.268G>C

1 paper

NM_001382430.1

p.V90M

c.268G>A

2 papers

NM_001382430.1

p.H89delFs

c.267delA

1 paper

NM_001382430.1

p.T87I

c.260C>T

1 paper

NM_001382430.1

p.V90A

c.269T>C