Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_001382430.1

p.E85K

c.253G>A

Surrounding Variants

1 paper

NM_001382430.1

p.E85*

c.253G>T

1 paper

NM_001382430.1

p.E85Q

c.253G>C

1 paper

NM_001382430.1

p.E85V

c.254A>T

1 paper

NM_001382430.1

p.E85A

c.254A>C

2 papers

NM_001382430.1

p.E85D

c.255A>T

2 papers

NM_001382430.1

p.R86C

c.256C>T

1 paper

NM_001382430.1

p.I84_E85delFs

c.251_255del5

1 paper

NM_001382430.1

p.I84F

c.250A>T

1 paper

NM_001382430.1

p.I84V

c.250A>G

1 paper

NM_001382430.1

p.I84_E85insT

c.250_254ins3

1 paper

NM_001382430.1

p.R86L

c.257G>T

7 papers

NM_001382430.1

p.R86H

c.257G>A