Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.V83F

c.247G>T

Surrounding Variants

1 paper

NM_001382430.1

p.I84F

c.250A>T

1 paper

NM_001382430.1

p.I84V

c.250A>G

1 paper

NM_001382430.1

p.T82insFs

c.244_245insT

1 paper

NM_001382430.1

p.I84_E85insT

c.250_254ins3

1 paper

NM_001382430.1

p.T81I

c.242C>T

1 paper

NM_001382430.1

p.E85*

c.253G>T

1 paper

NM_001382430.1

p.E85Q

c.253G>C

5 papers

NM_001382430.1

p.E85K

c.253G>A

1 paper

NM_001382430.1

p.T81S

c.241A>T

1 paper

NM_001382430.1

p.Q79_W80delFs

c.237_240del4

2 papers

NM_001382430.1

p.W80C

c.240G>T

2 papers

NM_001382430.1

p.W80C

c.240G>C