Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

72 papers

NM_001382430.1

p.Q79K

c.235C>A

Surrounding Variants

1 paper

NM_001382430.1

p.Q79*

c.235C>T

2 papers

NM_001382430.1

p.Q79E

c.235C>G

1 paper

NM_001382430.1

p.E66_L78ins4

c.196_234dup39

1 paper

NM_001382430.1

p.L78L

c.234G>T

4 papers

NM_001382430.1

p.Q79L

c.236A>T

6 papers

NM_001382430.1

p.Q79R

c.236A>G

1 paper

NM_001382430.1

p.Q79P

c.236A>C

1 paper

NM_001382430.1

p.R67_Q79ins4

c.200_235dup36

2 papers

NM_001382430.1

p.E66_L78ins4

c.197_232dup36

1 paper

NM_001382430.1

p.Q79insFs

c.237dupG

2 papers

NM_001382430.1

p.P68_Q79ins4

c.202_237dup36

1 paper

NM_001382430.1

p.R67_Q79ins4

c.199_237dup39