Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.L78L

c.232C>T

Surrounding Variants

1 paper

NM_001382430.1

p.L78fs

c.232_233fs

1 paper

NM_001382430.1

p.E66_C77ins4

c.196_231dup36

1 paper

NM_001382430.1

p.L78M

c.232C>A

2 papers

NM_001382430.1

p.E66_L78ins4

c.197_232dup36

2 papers

NM_001382430.1

p.R69_C77ins3

c.207_230dup24

1 paper

NM_001382430.1

p.R67_C77ins3

c.201_230dup30

1 paper

NM_001382430.1

p.K64_C77ins4

c.192_230dup39

9 papers

NM_001382430.1

p.C77F

c.230G>T

1 paper

NM_001382430.1

p.L78L

c.234G>T

2 papers

NM_001382430.1

p.Q61_R76ins5

c.181_228dup48

1 paper

NM_001382430.1

p.Q79*

c.235C>T

2 papers

NM_001382430.1

p.Q79E

c.235C>G