Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.F73C

c.218T>G

Surrounding Variants

1 paper

NM_001382430.1

p.I74N

c.221T>A

1 paper

NM_001382430.1

p.T72I

c.215C>T

2 papers

NM_001382430.1

p.T72S

c.215C>G

1 paper

NM_001382430.1

p.T72A

c.214A>G

1 paper

NM_001382430.1

p.I75F

c.223A>T

1 paper

NM_001382430.1

p.N71I

c.212A>T

4 papers

NM_001382430.1

p.I75M

c.225C>G

1 paper

NM_001382430.1

p.M63_I75ins4

c.189_224dup36

1 paper

NM_001382430.1

p.P68_R69del2

c.202_206del6

1 paper

NM_001382430.1

p.P68_P70del3

c.202_209del9

5 papers

NM_001382430.1

p.R76C

c.226C>T

1 paper

NM_001382430.1

p.R76ins12

c.226_227ins36