Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.P68_P70del3

c.202_209del9

Surrounding Variants

1 paper

NM_001382430.1

p.P68_R69del2

c.202_206del6

1 paper

NM_001382430.1

p.N71I

c.212A>T

1 paper

NM_001382430.1

p.P70L

c.209C>T

1 paper

NM_001382430.1

p.P70A

c.208C>G

1 paper

NM_001382430.1

p.P70_N71ins10

c.208_212ins30

1 paper

NM_001382430.1

p.T72A

c.214A>G

1 paper

NM_001382430.1

p.T72I

c.215C>T

2 papers

NM_001382430.1

p.T72S

c.215C>G

3 papers

NM_001382430.1

p.R69Q

c.206G>A

3 papers

NM_001382430.1

p.R69W

c.205C>T

1 paper

NM_001382430.1

p.R69G

c.205C>G

2 papers

NM_001382430.1

p.R69R

c.205C>A