Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.R67L

c.200G>T

Surrounding Variants

1 paper

NM_001382430.1

p.R67Q

c.200G>A

4 papers

NM_001382430.1

p.R67W

c.199C>T

1 paper

NM_001382430.1

p.T65_E66del2

c.193_197del6

1 paper

NM_001382430.1

p.E66D

c.198G>C

1 paper

NM_001382430.1

p.P68S

c.202C>T

1 paper

NM_001382430.1

p.R67_P68insFs

c.201_202insG

1 paper

NM_001382430.1

p.E66_R67insG

c.196_200ins3

1 paper

NM_001382430.1

p.E66Q

c.196G>C

3 papers

NM_001382430.1

p.R69W

c.205C>T

1 paper

NM_001382430.1

p.R69G

c.205C>G

2 papers

NM_001382430.1

p.R69R

c.205C>A

3 papers

NM_001382430.1

p.R69Q

c.206G>A