Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.M63L

c.187A>T

Surrounding Variants

1 paper

NM_001382430.1

p.M63L

c.187A>C

1 paper

NM_001382430.1

p.M63R

c.188T>G

2 papers

NM_001382430.1

p.M63K

c.188T>A

1 paper

NM_001382430.1

p.L62L

c.186G>C

1 paper

NM_001382430.1

p.L62insFs

c.184dupC

1 paper

NM_001382430.1

p.L62R

c.185T>G

1 paper

NM_001382430.1

p.L62P

c.185T>C

1 paper

NM_001382430.1

p.M63I

c.189G>T

1 paper

NM_001382430.1

p.M63I

c.189G>C

1 paper

NM_001382430.1

p.M63I

c.189G>A

1 paper

NM_001382430.1

p.M63delins

c.188_189delinsCT

1 paper

NM_001382430.1

p.K64fs

c.190_191fs