Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.Q59L

c.176A>T

Surrounding Variants

1 paper

NM_001382430.1

p.Q59E

c.175C>G

1 paper

NM_001382430.1

p.Q59K

c.175C>A

1 paper

NM_001382430.1

p.C60S

c.178T>A

1 paper

NM_001382430.1

p.C60S

c.179G>C

2 papers

NM_001382430.1

p.C60Y

c.179G>A

1 paper

NM_001382430.1

p.Q59Splc

c.176-3C>T

2 papers

NM_001382430.1

p.Q59Splc

c.176-4G>A

1 paper

NM_001382430.1

p.C60C

c.180C>T

2 papers

NM_001382430.1

p.C60*

c.180C>A

2 papers

NM_001382430.1

p.Q61*

c.181C>T

1 paper

NM_001382430.1

p.Q59Splc

c.176-5C>T

4 papers

NM_001382430.1

p.Q61E

c.181C>G