Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.A58E

c.173C>A

Surrounding Variants

3 papers

NM_001382430.1

p.A58V

c.173C>T

1 paper

NM_001382430.1

p.A58A

c.174G>T

1 paper

NM_001382430.1

p.A58S

c.172G>T

2 papers

NM_001382430.1

p.A58T

c.172G>A

1 paper

NM_001382430.1

p.A58A

c.174G>A

1 paper

NM_001382430.1

p.N53_A58del0

c.159_173del15

1 paper

NM_001382430.1

p.Q59_C60ins8

c.175_179ins24

1 paper

NM_001382430.1

p.Q59K

c.175C>A

2 papers

NM_001382430.1

p.V57E

c.170T>A

1 paper

NM_001382430.1

p.Q59insFs

c.175dupC

1 paper

NM_001382430.1

p.Q59Splc

c.175+1G>A

1 paper

NM_001382430.1

p.V57L

c.169G>T