Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

68 papers

NM_001382430.1

p.L52R

c.155T>G

Surrounding Variants

2 papers

NM_001382430.1

p.L52P

c.155T>C

8 papers

NM_001382430.1

p.L52H

c.155T>A

1 paper

NM_001382430.1

p.P51delFs

c.153delG

2 papers

NM_001382430.1

p.L52F

c.154C>T

1 paper

NM_001382430.1

p.L52fs

c.154_155fs

1 paper

NM_001382430.1

p.L52I

c.154C>A

1 paper

NM_001382430.1

p.P51P

c.153C>T

2 papers

NM_001382430.1

p.N53Y

c.157A>T

3 papers

NM_001382430.1

p.N53H

c.157A>C

9 papers

NM_001382430.1

p.P51L

c.152C>T

5 papers

NM_001382430.1

p.P51S

c.151C>T

1 paper

NM_001382430.1

p.A50A

c.150T>A