Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

37 papers

NM_001382430.1

p.E49K

c.145G>A

Surrounding Variants

1 paper

NM_001382430.1

p.E49*

c.145G>T

1 paper

NM_001382430.1

p.E49Q

c.145G>C

1 paper

NM_001382430.1

p.R48R

c.144T>C

10 papers

NM_001382430.1

p.E49V

c.146A>T

1 paper

NM_001382430.1

p.E49G

c.146A>G

1 paper

NM_001382430.1

p.E49A

c.146A>C

1 paper

NM_001382430.1

p.E49D

c.147G>T

1 paper

NM_001382430.1

p.E49D

c.147G>C

6 papers

NM_001382430.1

p.R48H

c.143G>A

1 paper

NM_001382430.1

p.E49E

c.147G>A

3 papers

NM_001382430.1

p.R48C

c.142C>T

3 papers

NM_001382430.1

p.A50V

c.149C>T