Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.V45V

c.135G>T

Surrounding Variants

2 papers

NM_001382430.1

p.V45A

c.134T>C

1 paper

NM_001382430.1

p.D44del1

c.130_131delATC

1 paper

NM_001382430.1

p.D46H

c.136G>C

2 papers

NM_001382430.1

p.D46N

c.136G>A

1 paper

NM_001382430.1

p.V45delFs

c.133_134delAC

3 papers

NM_001382430.1

p.V45M

c.133G>A

1 paper

NM_001382430.1

p.D44E

c.132T>G

1 paper

NM_001382430.1

p.D44E

c.132T>A

18 papers

NM_001382430.1

p.D46E

c.138C>G

18 papers

NM_001382430.1

p.D46E

c.138C>A

3 papers

NM_001382430.1

p.Q47*

c.139C>T

1 paper

NM_001382430.1

p.Q47K

c.139C>A