Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_001382430.1

p.P42T

c.124C>A

Surrounding Variants

3 papers

NM_001382430.1

p.P42S

c.124C>T

2 papers

NM_001382430.1

p.P42A

c.124C>G

1 paper

NM_001382430.1

p.R41R

c.123G>T

2 papers

NM_001382430.1

p.P42L

c.125C>T

2 papers

NM_001382430.1

p.P42Q

c.125C>A

1 paper

NM_001382430.1

p.P42P

c.126G>C

2 papers

NM_001382430.1

p.R41Q

c.122G>A

1 paper

NM_001382430.1

p.P42P

c.126G>A

6 papers

NM_001382430.1

p.R41W

c.121C>T

3 papers

NM_001382430.1

p.Q43*

c.127C>T

3 papers

NM_001382430.1

p.Q43K

c.127C>A

1 paper

NM_001382430.1

p.E40E

c.120G>A