Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.Y38N

c.112T>A

Surrounding Variants

2 papers

NM_001382430.1

p.Y38H

c.112T>C

1 paper

NM_001382430.1

p.Y38F

c.113A>T

2 papers

NM_001382430.1

p.Y38C

c.113A>G

1 paper

NM_001382430.1

p.Y38insFs

c.113_114insG

6 papers

NM_001382430.1

p.G37D

c.110G>A

1 paper

NM_001382430.1

p.G37C

c.109G>T

1 paper

NM_001382430.1

p.G37insFs

c.109_110ins5

1 paper

NM_001382430.1

p.K39E

c.115A>G

1 paper

NM_001382430.1

p.G37_Y38delFs

c.110_114del5

1 paper

NM_001382430.1

p.I36M

c.108T>G

1 paper

NM_001382430.1

p.K39R

c.116A>G

1 paper

NM_001382430.1

p.I36T

c.107T>C