Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_001382430.1

p.F35L

c.105C>G

Surrounding Variants

6 papers

NM_001382430.1

p.F35L

c.105C>A

1 paper

NM_001382430.1

p.F35S

c.104T>C

1 paper

NM_001382430.1

p.F35Y

c.104T>A

2 papers

NM_001382430.1

p.I36V

c.106A>G

8 papers

NM_001382430.1

p.F35L

c.103T>C

1 paper

NM_001382430.1

p.I36T

c.107T>C

3 papers

NM_001382430.1

p.F35I

c.103T>A

1 paper

NM_001382430.1

p.I36M

c.108T>G

1 paper

NM_001382430.1

p.G37C

c.109G>T

1 paper

NM_001382430.1

p.G37insFs

c.109_110ins5

3 papers

NM_001382430.1

p.T34I

c.101C>T

1 paper

NM_001382430.1

p.T34N

c.101C>A