Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001382430.1

p.L28P

c.83T>C

Surrounding Variants

4 papers

NM_001382430.1

p.L28F

c.82C>T

1 paper

NM_001382430.1

p.L28L

c.84C>T

1 paper

NM_001382430.1

p.L28V

c.82C>G

1 paper

NM_001382430.1

p.L28_L29insFs

c.84_85insT

2 papers

NM_001382430.1

p.L29F

c.85C>T

2 papers

NM_001382430.1

p.L29V

c.85C>G

2 papers

NM_001382430.1

p.F27L

c.81C>G

1 paper

NM_001382430.1

p.F27insFs

c.79dupT

1 paper

NM_001382430.1

p.F27fs

c.79_80fs

2 papers

NM_001382430.1

p.F27L

c.81C>A

1 paper

NM_001382430.1

p.L29P

c.86T>C

1 paper

NM_001382430.1

p.F27Y

c.80T>A