Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

11 papers

NM_001382430.1

p.R23Q

c.68G>A

Surrounding Variants

2 papers

NM_001382430.1

p.R23L

c.68G>T

5 papers

NM_001382430.1

p.R23W

c.67C>T

1 paper

NM_001382430.1

p.W22_R23insFs

c.66_67insG

1 paper

NM_001382430.1

p.W22delFs

c.65_66delCC

1 paper

NM_001382430.1

p.W22C

c.66G>T

2 papers

NM_001382430.1

p.W22*

c.66G>A

1 paper

NM_001382430.1

p.P24S

c.70C>T

1 paper

NM_001382430.1

p.P24A

c.70C>G

1 paper

NM_001382430.1

p.P24insFs

c.70_71ins10

1 paper

NM_001382430.1

p.P24T

c.70C>A

1 paper

NM_001382430.1

p.R23delFs

c.68_69delCC

1 paper

NM_001382430.1

p.P24fs

c.70_71fs