Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.K20E

c.58A>G

Surrounding Variants

1 paper

NM_001382430.1

p.K20*

c.58A>T

2 papers

NM_001382430.1

p.K20Q

c.58A>C

8 papers

NM_001382430.1

p.K20M

c.59A>T

5 papers

NM_001382430.1

p.K20R

c.59A>G

1 paper

NM_001382430.1

p.Y18delFs

c.53_54delGT

1 paper

NM_001382430.1

p.I19F

c.55A>T

4 papers

NM_001382430.1

p.T21A

c.61A>G

1 paper

NM_001382430.1

p.I19L

c.55A>C

1 paper

NM_001382430.1

p.I19insFs

c.55_56insT

5 papers

NM_001382430.1

p.T21I

c.62C>T

1 paper

NM_001382430.1

p.Y18_I19insFs

c.54_55insT

1 paper

NM_001382430.1

p.Y18fs

c.52_53fs