Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.K14N

c.42A>C

Surrounding Variants

2 papers

NM_001382430.1

p.K14N

c.42A>T

1 paper

NM_001382430.1

p.R15R

c.43C>A

2 papers

NM_001382430.1

p.K14I

c.41A>T

3 papers

NM_001382430.1

p.K14R

c.41A>G

1 paper

NM_001382430.1

p.R15L

c.44G>T

1 paper

NM_001382430.1

p.R15P

c.44G>C

11 papers

NM_001382430.1

p.R15Q

c.44G>A

2 papers

NM_001382430.1

p.K14Q

c.40A>C

1 paper

NM_001382430.1

p.H13Q

c.39C>G

1 paper

NM_001382430.1

p.G16R

c.46G>A

1 paper

NM_001382430.1

p.H13insFs

c.38_39insG

2 papers

NM_001382430.1

p.G16Splc

c.46+1G>A