Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.W11*

c.32G>A

Surrounding Variants

1 paper

NM_001382430.1

p.W11*

c.33G>A

1 paper

NM_001382430.1

p.L12L

c.34C>T

1 paper

NM_001382430.1

p.L12V

c.34C>G

1 paper

NM_001382430.1

p.L12R

c.35T>G

2 papers

NM_001382430.1

p.L12Q

c.35T>A

2 papers

NM_001382430.1

p.G10V

c.29G>T

1 paper

NM_001382430.1

p.G10C

c.28G>T

1 paper

NM_001382430.1

p.G10R

c.28G>C

2 papers

NM_001382430.1

p.G10S

c.28G>A

1 paper

NM_001382430.1

p.L12L

c.36G>A

1 paper

NM_001382430.1

p.H13Y

c.37C>T

1 paper

NM_001382430.1

p.E9G

c.26A>G