Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001382430.1

p.K8*

c.22A>T

Surrounding Variants

2 papers

NM_001382430.1

p.K8E

c.22A>G

3 papers

NM_001382430.1

p.K8R

c.23A>G

1 paper

NM_001382430.1

p.K8T

c.23A>C

1 paper

NM_001382430.1

p.V7A

c.20T>C

1 paper

NM_001382430.1

p.V7E

c.20T>A

1 paper

NM_001382430.1

p.V7L

c.19G>T

1 paper

NM_001382430.1

p.V7M

c.19G>A

1 paper

NM_001382430.1

p.E9G

c.26A>G

1 paper

NM_001382430.1

p.I6T

c.17T>C

1 paper

NM_001382430.1

p.I6delFs

c.16delT

1 paper

NM_001382430.1

p.G10C

c.28G>T

1 paper

NM_001382430.1

p.G10R

c.28G>C