Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001382430.1

p.A5T

c.13G>A

Surrounding Variants

8 papers

NM_001382430.1

p.A5P

c.13G>C

39 papers

NM_001382430.1

p.V4V

c.12G>C

29 papers

NM_001382430.1

p.V4V

c.12G>A

1 paper

NM_001382430.1

p.A5V

c.14C>T

2 papers

NM_001382430.1

p.A5G

c.14C>G

1 paper

NM_001382430.1

p.V4A

c.11T>C

4 papers

NM_001382430.1

p.V4L

c.10G>T

4 papers

NM_001382430.1

p.V4L

c.10G>C

2 papers

NM_001382430.1

p.V4M

c.10G>A

1 paper

NM_001382430.1

p.I6V

c.16A>G

1 paper

NM_001382430.1

p.I6T

c.17T>C

1 paper

NM_001382430.1

p.I6delFs

c.16delT