Varaico: Literature-Extracted Genetic Variants

Gene:AKT2
Variant:p.R480G

AKT2

617 papers

RefSeq Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The...

Pfam Domains

PHaa 6–108UCSCPH domain
Pkinaseaa 152–409UCSCProtein kinase domain
Pkinase_Caa 430–475UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 2

HGNC Alias Symbol

PKBβ

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001626.6
p.R480G
c.1438C>G
Surrounding Variants
4 papers
NM_001626.6
p.R480C
c.1438C>T
2 papers
NM_001626.6
p.R480H
c.1439G>A
1 paper
NM_001626.6
p.Y475C
c.1424A>G
1 paper
NM_001626.6
p.Y475S
c.1424A>C
1 paper
NM_001626.6
p.S474F
c.1421C>T
3 papers
NM_001626.6
p.S474A
c.1420T>G
1 paper
NM_001626.6
p.P471S
c.1411C>T
1 paper
NM_001626.6
p.F470I
c.1408T>A
1 paper
NM_001626.6
p.T468A
c.1402A>G
1 paper
NM_001626.6
p.R467Q
c.1400G>A
9 papers
NM_001626.6
p.R467W
c.1399C>T
1 paper
NM_001626.6
p.G460D
c.1379G>A
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