Varaico: Literature-Extracted Genetic Variants

Gene:AKT2
Variant:p.D388N

AKT2

617 papers

RefSeq Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The...

Pfam Domains

PHaa 6–108UCSCPH domain
Pkinaseaa 152–409UCSCProtein kinase domain
Pkinase_Caa 430–475UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 2

HGNC Alias Symbol

PKBβ

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001626.6
p.D388N
c.1162G>A
Surrounding Variants
1 paper
NM_001243027.3
p.D326Y
c.976G>T
1 paper
NM_001626.6
p.K387E
c.1159A>G
1 paper
NM_001626.6
p.K386N
c.1158G>T
1 paper
NM_001626.6
p.K386N
c.1158G>C
1 paper
NM_001626.6
p.K386T
c.1157A>C
1 paper
NM_001626.6
p.K390E
c.1168A>G
1 paper
NM_001626.6
p.L385H
c.1154T>A
1 paper
NM_001626.6
p.G383R
c.1147G>A
1 paper
NM_001626.6
p.A382S
c.1144G>T
1 paper
NM_001626.6
p.A382T
c.1144G>A
1 paper
NM_001626.6
p.S379S
c.1137C>A
1 paper
NM_001626.6
p.S379F
c.1136C>T
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