Varaico: Literature-Extracted Genetic Variants

Gene:AKT2
Variant:p.R371H

AKT2

617 papers

RefSeq Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The...

Pfam Domains

PHaa 6–108UCSCPH domain
Pkinaseaa 152–409UCSCProtein kinase domain
Pkinase_Caa 430–475UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 2

HGNC Alias Symbol

PKBβ

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
17 papers
NM_001626.6
p.R371H
c.1112G>A
Surrounding Variants
4 papers
NM_001626.6
p.R371C
c.1111C>T
2 papers
NM_001626.6
p.P370P
c.1110G>T
3 papers
NM_001626.6
p.T372M
c.1115C>T
1 paper
NM_001626.6
p.P370L
c.1109C>T
1 paper
NM_001626.6
p.P370Q
c.1109C>A
1 paper
NM_001626.6
p.L373F
c.1117C>T
1 paper
NM_001626.6
p.S374C
c.1120A>T
2 papers
NM_001626.6
p.R368H
c.1103G>A
3 papers
NM_001626.6
p.R368C
c.1102C>T
1 paper
NM_001626.6
p.E365D
c.1095A>T
1 paper
NM_001626.6
p.E365D
c.1095A>C
3 papers
NM_001626.6
p.A377V
c.1130C>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."