Varaico: Literature-Extracted Genetic Variants

Gene:AKT2
Variant:p.W333R

AKT2

617 papers

RefSeq Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The...

Pfam Domains

PHaa 6–108UCSCPH domain
Pkinaseaa 152–409UCSCProtein kinase domain
Pkinase_Caa 430–475UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 2

HGNC Alias Symbol

PKBβ

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001626.6
p.W333R
c.997T>C
Surrounding Variants
1 paper
NM_001626.6
p.W333R
c.997T>A
1 paper
NM_001626.6
p.W333*
c.998G>A
1 paper
NM_001626.6
p.D332D
c.996C>T
1 paper
NM_001626.6
p.D332E
c.996C>G
1 paper
NM_001626.6
p.D332E
c.996C>A
1 paper
NM_001626.6
p.W333*
c.999G>A
1 paper
NM_001626.6
p.W334L
c.1001G>T
1 paper
NM_001626.6
p.V331V
c.993G>A
1 paper
NM_001626.6
p.G335Fs
c.1003delinsGAFs
1 paper
NM_001626.6
p.G335E
c.1004G>A
1 paper
NM_001626.6
p.A330V
c.989C>T
1 paper
NM_001626.6
p.A330T
c.988G>A
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