Varaico: Literature-Extracted Genetic Variants

Gene:AKT2
Variant:p.D326Y

AKT2

617 papers

RefSeq Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The...

Pfam Domains

PHaa 6–108UCSCPH domain
Pkinaseaa 152–409UCSCProtein kinase domain
Pkinase_Caa 430–475UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 2

HGNC Alias Symbol

PKBβ

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001626.6
p.D326Y
c.976G>T
Surrounding Variants
1 paper
NM_001626.6
p.D326H
c.976G>C
1 paper
NM_001626.6
p.D326N
c.976G>A
1 paper
NM_001626.6
p.N325S
c.974A>G
1 paper
NM_001243027.3
p.Y265N
c.793T>A
2 papers
NM_001626.6
p.Y327Y
c.981T>C
5 papers
NM_001626.6
p.D324G
c.971A>G
3 papers
NM_001626.6
p.D324H
c.970G>C
1 paper
NM_001626.6
p.D324N
c.970G>A
1 paper
NM_001626.6
p.E323D
c.969G>T
1 paper
NM_001626.6
p.D326_G328ins1
c.977_982dup6
1 paper
NM_001626.6
p.E323D
c.969G>C
1 paper
NM_001626.6
p.E323Q
c.967G>C
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