Varaico: Literature-Extracted Genetic Variants

Gene:AKT2
Variant:p.F294S

AKT2

617 papers

RefSeq Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The...

Pfam Domains

PHaa 6–108UCSCPH domain
Pkinaseaa 152–409UCSCProtein kinase domain
Pkinase_Caa 430–475UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 2

HGNC Alias Symbol

PKBβ

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001626.6
p.F294S
c.881T>C
Surrounding Variants
1 paper
NM_001626.6
p.G295D
c.884G>A
1 paper
NM_001626.6
p.D293_G295delins
c.879_885delinsT
1 paper
NM_001626.6
p.K290delFs
c.868delT
3 papers
NM_001626.6
p.K290R
c.869A>G
1 paper
NM_001626.6
p.E299K
c.895G>A
4 papers
NM_001626.6
p.I289M
c.867C>G
1 paper
NM_001626.6
p.E299D
c.897G>T
1 paper
NM_001626.6
p.E299D
c.897G>C
1 paper
NM_001626.6
p.I301fs
c.901_902fs
12 papers
NM_001626.6
p.S302G
c.904A>G
1 paper
NM_001626.6
p.D286N
c.856G>A
1 paper
NM_001626.6
p.K285N
c.855A>T
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