Varaico: Literature-Extracted Genetic Variants

Gene:AKT2
Variant:p.N71_T72insFs

AKT2

617 papers

RefSeq Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The...

Pfam Domains

PHaa 6–108UCSCPH domain
Pkinaseaa 152–409UCSCProtein kinase domain
Pkinase_Caa 430–475UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 2

HGNC Alias Symbol

PKBβ

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001626.6
p.N71_T72insFs
c.213_214insT
Surrounding Variants
1 paper
NM_001626.6
p.N71N
c.213C>T
1 paper
NM_001626.6
p.N71S
c.212A>G
1 paper
NM_001626.6
p.F73V
c.217T>G
1 paper
NM_001626.6
p.V74F
c.220G>T
2 papers
NM_001626.6
p.R69Q
c.206G>A
2 papers
NM_001626.6
p.P68L
c.203C>T
1 paper
NM_001626.6
p.R76H
c.227G>A
1 paper
NM_001626.6
p.R76R
c.228C>T
1 paper
NM_001626.6
p.C77S
c.229T>A
1 paper
NM_001626.6
p.C77F
c.230G>T
1 paper
NM_001626.6
p.C77S
c.230G>C
1 paper
NM_001626.6
p.C77C
c.231C>T
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