Varaico: Literature-Extracted Genetic Variants

Gene:AKT2
Variant:p.V57I

AKT2

617 papers

RefSeq Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The...

Pfam Domains

PHaa 6–108UCSCPH domain
Pkinaseaa 152–409UCSCProtein kinase domain
Pkinase_Caa 430–475UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 2

HGNC Alias Symbol

PKBβ

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_001626.6
p.V57I
c.169G>A
Surrounding Variants
1 paper
NM_001626.6
p.V57L
c.169G>T
1 paper
NM_001626.6
p.V57L
c.169G>C
2 papers
NM_001626.6
p.S56F
c.167C>T
1 paper
NM_001626.6
p.A58T
c.172G>A
2 papers
NM_001626.6
p.F55L
c.165C>G
2 papers
NM_001626.6
p.F55L
c.165C>A
1 paper
NM_001626.6
p.F55Y
c.164T>A
2 papers
NM_001626.6
p.F55L
c.163T>C
1 paper
NM_001626.6
p.F55I
c.163T>A
1 paper
NM_001626.6
p.E59insFs
c.175dupG
1 paper
NM_001626.6
p.N53Y
c.157A>T
1 paper
NM_001626.6
p.N53H
c.157A>C
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."