Varaico: Literature-Extracted Genetic Variants

Gene:AKT2
Variant:p.K20_R25insFs

AKT2

617 papers

RefSeq Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The...

Pfam Domains

PHaa 6–108UCSCPH domain
Pkinaseaa 152–409UCSCProtein kinase domain
Pkinase_Caa 430–475UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 2

HGNC Alias Symbol

PKBβ

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001626.6
p.K20_R25insFs
c.60_75dup16
Surrounding Variants
2 papers
NM_001626.6
p.Y26H
c.76T>C
1 paper
NM_001626.6
p.Y26C
c.77A>G
1 paper
NM_001626.6
p.Y26S
c.77A>C
2 papers
NM_001626.6
p.R25Q
c.74G>A
1 paper
NM_001626.6
p.Y26insFs
c.77dupA
1 paper
NM_001626.6
p.R23_Y26ins1
c.67_78dup12
1 paper
NM_001626.6
p.F27L
c.79T>C
1 paper
NM_001626.6
p.R25W
c.73C>T
1 paper
NM_001626.6
p.F27Y
c.80T>A
1 paper
NM_001626.6
p.F27L
c.81C>G
1 paper
NM_001626.6
p.F27insFs
c.79dupT
1 paper
NM_001626.6
p.R23_F27insFs
c.68_80dup13
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