Varaico: Literature-Extracted Genetic Variants

Gene:AKT2
Variant:p.I19M

AKT2

617 papers

RefSeq Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The...

Pfam Domains

PHaa 6–108UCSCPH domain
Pkinaseaa 152–409UCSCProtein kinase domain
Pkinase_Caa 430–475UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 2

HGNC Alias Symbol

PKBβ

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001626.6
p.I19M
c.57C>G
Surrounding Variants
1 paper
NM_001626.6
p.I19T
c.56T>C
1 paper
NM_001626.6
p.K20*
c.58A>T
1 paper
NM_001626.6
p.K20M
c.59A>T
1 paper
NM_001626.6
p.Y18F
c.53A>T
1 paper
NM_001626.6
p.Y18S
c.53A>C
1 paper
NM_001626.6
p.W22R
c.64T>C
1 paper
NM_001626.6
p.W22R
c.64T>A
46 papers
NM_001626.6
p.E17K
c.49G>A
1 paper
NM_001626.6
p.G16D
c.47G>A
1 paper
NM_001626.6
p.P24S
c.70C>T
1 paper
NM_001626.6
p.R25W
c.73C>T
2 papers
NM_001626.6
p.R25Q
c.74G>A
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