Varaico: Literature-Extracted Genetic Variants

Gene:AKT2
Variant:p.M1_N2insFs

AKT2

617 papers

RefSeq Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The...

Pfam Domains

PHaa 6–108UCSCPH domain
Pkinaseaa 152–409UCSCProtein kinase domain
Pkinase_Caa 430–475UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 2

HGNC Alias Symbol

PKBβ

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001626.6
p.M1_N2insFs
c.3_4insA
Surrounding Variants
1 paper
NM_001626.6
p.E3delFs
c.7delC
1 paper
NM_001626.6
p.E3D
c.9G>T
1 paper
NM_001626.6
p.V4M
c.10G>A
9 papers
NM_001626.6
p.V4V
c.12G>C
7 papers
NM_001626.6
p.V4V
c.12G>A
2 papers
NM_001626.6
p.V6A
c.17T>C
2 papers
NM_001626.6
p.E9G
c.26A>G
1 paper
NM_001626.6
p.G10V
c.29G>T
1 paper
NM_001626.6
p.W11*
c.32G>A
1 paper
NM_001626.6
p.W11*
c.33G>A
1 paper
NM_001626.6
p.K14T
c.41A>C
1 paper
NM_001626.6
p.R15C
c.43C>T
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