Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005465.7

p.R464K

c.1391G>A

Surrounding Variants

30 papers

NM_005465.7

p.R465W

c.1393C>T

2 papers

NM_005465.7

p.R465Q

c.1394G>A

2 papers

NM_005465.7

p.P466L

c.1397C>T

1 paper

NM_005465.7

p.D461G

c.1382A>G

1 paper

NM_005465.7

p.D461N

c.1381G>A

1 paper

NM_005465.7

p.M460I

c.1380G>T

1 paper

NM_005465.7

p.M460I

c.1380G>C

1 paper

NM_005465.7

p.M460I

c.1380G>A

1 paper

NM_005465.7

p.M460R

c.1379T>G

1 paper

NM_005465.7

p.C459Y

c.1376G>A

1 paper

NM_005465.7

p.Q470*

c.1408C>T

4 papers

NM_005465.7

p.S472A

c.1414T>G