Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005465.7

p.K383K

c.1149G>A

Surrounding Variants

1 paper

NM_005465.7

p.D384N

c.1150G>A

1 paper

NM_005465.7

p.P385S

c.1153C>T

1 paper

NM_005465.7

p.P385T

c.1153C>A

1 paper

NM_005465.7

p.P385Q

c.1154C>A

1 paper

NM_005465.7

p.L380F

c.1138C>T

2 papers

NM_005465.7

p.G379G

c.1137G>A

1 paper

NM_005465.7

p.R388C

c.1162C>T

3 papers

NM_005465.7

p.S375*

c.1124C>G

3 papers

NM_005465.7

p.S375*

c.1124C>A

1 paper

NM_005465.7

p.R388Splc

c.1163+16C>T

2 papers

NM_005465.7

p.A373G

c.1118C>G

1 paper

NM_005465.7

p.A373T

c.1117G>A