Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005465.7

p.S370Y

c.1109C>A

Surrounding Variants

1 paper

NM_005465.7

p.S371L

c.1112C>T

1 paper

NM_005465.7

p.L369F

c.1105C>T

1 paper

NM_005465.7

p.D372fs

c.1114_1115fs

1 paper

NM_005465.7

p.D372delFs

c.1114delC

1 paper

NM_005465.7

p.A373T

c.1117G>A

2 papers

NM_005465.7

p.R367Q

c.1100G>A

2 papers

NM_005465.7

p.A373G

c.1118C>G

1 paper

NM_005465.7

p.R367*

c.1099C>T

3 papers

NM_005465.7

p.P366S

c.1096C>T

3 papers

NM_005465.7

p.S375*

c.1124C>G

3 papers

NM_005465.7

p.S375*

c.1124C>A

1 paper

NM_005465.7

p.D362A

c.1085A>C