Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005465.7

p.Y347*

c.1041C>A

Surrounding Variants

1 paper

NM_005465.7

p.Y347*

c.1041C>G

1 paper

NM_005465.7

p.F346F

c.1038C>T

1 paper

NM_005465.7

p.Q349K

c.1045C>A

1 paper

NM_005465.7

p.Q349L

c.1046A>T

1 paper

NM_005465.7

p.Q349insFs

c.1046dupA

1 paper

NM_005465.7

p.P345fs

c.1033_1034fs

1 paper

NM_005465.7

p.P345S

c.1033C>T

1 paper

NM_005465.7

p.R343M

c.1028G>T

2 papers

NM_005465.7

p.E352K

c.1054G>A

5 papers

NM_005465.7

p.E352D

c.1056G>T

5 papers

NM_005465.7

p.E352D

c.1056G>C

2 papers

NM_005465.7

p.K353Q

c.1057A>C