Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005465.7

p.M336I

c.1008G>T

Surrounding Variants

1 paper

NM_005465.7

p.M336I

c.1008G>C

1 paper

NM_005465.7

p.M336I

c.1008G>A

2 papers

NM_005465.7

p.M336V

c.1006A>G

1 paper

NM_005465.7

p.V335Fs

c.1003delinsGAFs

1 paper

NM_005465.7

p.E338K

c.1012G>A

1 paper

NM_005465.7

p.V334D

c.1001T>A

1 paper

NM_005465.7

p.G342W

c.1024G>T

1 paper

NM_005465.7

p.G331V

c.992G>T

1 paper

NM_005465.7

p.G331D

c.992G>A

1 paper

NM_005465.7

p.R343M

c.1028G>T

1 paper

NM_005465.7

p.P345fs

c.1033_1034fs

1 paper

NM_005465.7

p.P345S

c.1033C>T