Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005465.7

p.D322V

c.965A>T

Surrounding Variants

4 papers

NM_005465.7

p.D322G

c.965A>G

3 papers

NM_005465.7

p.D322Y

c.964G>T

10 papers

NM_005465.7

p.D322N

c.964G>A

2 papers

NM_005465.7

p.N321K

c.963T>G

2 papers

NM_005465.7

p.N321K

c.963T>A

1 paper

NM_005465.7

p.D320Y

c.958G>T

1 paper

NM_005465.7

p.D320H

c.958G>C

3 papers

NM_005465.7

p.R325*

c.973C>T

1 paper

NM_005465.7

p.R325L

c.974G>T

2 papers

NM_005465.7

p.R325Q

c.974G>A

2 papers

NM_005465.7

p.E319G

c.956A>G

1 paper

NM_005465.7

p.L318*

c.953T>A