Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005465.7

p.N229H

c.685A>C

Surrounding Variants

15 papers

NM_005465.7

p.N229S

c.686A>G

1 paper

NM_005465.7

p.N229T

c.686A>C

2 papers

NM_005465.7

p.G230V

c.689G>T

1 paper

NM_005465.7

p.G231insFs

c.692dupG

1 paper

NM_005465.7

p.E226G

c.677A>G

1 paper

NM_005465.7

p.E226Q

c.676G>C

1 paper

NM_005465.7

p.E232K

c.694G>A

1 paper

NM_005465.7

p.E232fs

c.694_695fs

1 paper

NM_005465.7

p.E232_L233Splc

c.696+3G>A

1 paper

NM_005465.7

p.C222G

c.664T>G

4 papers

NM_005465.7

p.R220H

c.659G>A

4 papers

NM_005465.7

p.D219V

c.656A>T