Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005465.7

p.I184V

c.550A>G

Surrounding Variants

1 paper

NM_005465.7

p.I184M

c.552T>G

14 papers

NM_005465.7

p.V183D

c.548T>A

1 paper

NM_005465.7

p.E182D

c.546A>T

1 paper

NM_005465.7

p.E182D

c.546A>C

1 paper

NM_005465.7

p.E182G

c.545A>G

1 paper

NM_005465.7

p.E182A

c.545A>C

2 papers

NM_005465.7

p.E182*

c.544G>T

1 paper

NM_005465.7

p.A186E

c.557C>A

1 paper

NM_005465.7

p.K180R

c.539A>G

2 papers

NM_005465.7

p.K180E

c.538A>G

3 papers

NM_005465.7

p.K180Q

c.538A>C

4 papers

NM_005465.7

p.K177M

c.530A>T