Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005465.7

p.T144T

c.432A>G

Surrounding Variants

1 paper

NM_005465.7

p.M145V

c.433A>G

1 paper

NM_005465.7

p.M145K

c.434T>A

1 paper

NM_005465.7

p.N146fs

c.436_437fs

1 paper

NM_005465.7

p.N146_D147delFs

c.437_440del4

1 paper

NM_005465.7

p.Y150F

c.449A>T

1 paper

NM_005465.7

p.L151F

c.453G>T

1 paper

NM_005465.7

p.L151F

c.453G>C

1 paper

NM_005465.7

p.K152R

c.455A>G

1 paper

NM_005465.7

p.N146_L153delFs

c.436_458del23

1 paper

NM_005465.7

p.G155_K156ins5

c.463_467ins15

1 paper

NM_005465.7

p.G155S

c.463G>A

1 paper

NM_005465.7

p.K156E

c.466A>G