Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005465.7

p.T81I

c.242C>T

Surrounding Variants

2 papers

NM_005465.7

p.T81ins0

c.241_243dupACT

2 papers

NM_005465.7

p.T80A

c.238A>G

1 paper

NM_005465.7

p.T80P

c.238A>C

1 paper

NM_005465.7

p.W79delFs

c.236delC

7 papers

NM_005465.7

p.W79C

c.237G>T

7 papers

NM_005465.7

p.W79C

c.237G>C

1 paper

NM_005465.7

p.I83L

c.247A>T

1 paper

NM_005465.7

p.I83L

c.247A>C

1 paper

NM_005465.7

p.W79G

c.235T>G

1 paper

NM_005465.7

p.W79R

c.235T>A

3 papers

NM_005465.7

p.E84K

c.250G>A

2 papers

NM_005465.7

p.Q78R

c.233A>G