Varaico: Literature-Extracted Genetic Variants

AKT3

598 papers

RefSeq Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and g...

Pfam Domains

PHaa 6–107UCSCPH domain

Pkinaseaa 148–405UCSCProtein kinase domain

Pkinase_Caa 426–473UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 3

HGNC Alias Symbols

PKBG; RAC-gamma; PRKBG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005465.7

p.T64T

c.192A>T

Surrounding Variants

1 paper

NM_005465.7

p.E65K

c.193G>A

4 papers

NM_005465.7

p.R66*

c.196C>T

1 paper

NM_005465.7

p.K63I

c.188A>T

3 papers

NM_005465.7

p.R66L

c.197G>T

1 paper

NM_005465.7

p.R66Q

c.197G>A

1 paper

NM_005465.7

p.M62I

c.186G>T

1 paper

NM_005465.7

p.M62I

c.186G>C

1 paper

NM_005465.7

p.M62I

c.186G>A

1 paper

NM_005465.7

p.E65_R66del2

c.193_197del6

1 paper

NM_005465.7

p.L61F

c.183A>C

1 paper

NM_005465.7

p.Q60H

c.180G>T

1 paper

NM_005465.7

p.Q60H

c.180G>C